Page 16 - NUTRINSIGHT-5-HD

NutrInsight • Slow-release carbohydrates: Growing evidence on metabolic responses and public health interest

High SDS content improves cardiovascular risk factors

In the same clinical trial, the influence of medium-term low GI and high GI diets on body weight and fasting
blood lipids concentrations was also assessed. The overweight normo-glycemic subjects followed an ad libitum
diet for five weeks, during which time they were asked to replace all starches in their normal diet with either
low GI or high GI starchy foods. High SDS (low GI) or very low SDS (high GI) breakfast cereal products were
provided to the subjects. The 5-week low GI diet was responsible for a small but significant decrease in body
weight (the mean weight loss was around 1 kg) and body mass index (BMI) (see Figure 10). This can contribute
to weight maintenance in overweight subjects. This 5-week low GI intervention diet was also associated
with an improvement in blood lipid profiles, as demonstrated by changes in fasting plasma total cholesterol,
LDL-cholesterol, total/HDL-cholesterol and LDL-/HDL-cholesterol (see Figure 11) [de Rougemont et al., 2007].

Figure 10: Changes in body weight and body mass index (BMI) after five weeks of an ad libitum
low glycemic index (GI) (in black; n=19) or high GI (in white; n=19) diet in overweight subjects.
There were no differences in body weight at baseline between the groups. Significant differences in
body weight and BMI changes between groups were identified by analysis of covariance using the
baseline as the covariate (* P=0.04 and ** P=0.03, respectively).
Source: de Rougemont et al., 2007

16